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Gibco™ Mouse Noggin, Animal-Free Recombinant Protein, PeproTech®
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Mængde:
100 μg
2 x 500 μg
20 μg
500 μg
Beskrivelse
AF-250-38-1MG will be provided as 2 x 500 μg (AF-250-38-500UG). Recombinant Murine Noggin is a 46.4 kDa disulfide-linked homodimer consisting of two 206 amino acid polypeptide chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
Tekniske data
Tekniske data
| Adgangsnummer | P97466 |
| Til brug med (applikation) | Functional Assay |
| Formulering | protein with no preservative |
| Gen-id (Entrez) | 18121 |
| Molekylvægt (g/mol) | 46.4 |
| Navn | Mouse Noggin, Animal-Free |
| Mængde | 2 x 500 μg |
| Kilde | E. coli |
| Opbevaringskrav | -20°C |
| Regulatorisk status | RUO |
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