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Gibco™ Mouse FGF-23 Recombinant Protein, PeproTech®

Artikelnummer. 17814363
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Mængde:
100 μg
2 x 500 μg
20 μg
250 μg
5 μg
500 μg
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Artikelnummer. 17814363

Brand: Gibco™ 45055100UG

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Beskrivelse

Recombinant Protein

450-55-1MG will be provided as 2 x 500 μg (450-55-500UG). Recombinant Murine FGF-23 is a 25.5 kDa globular protein containing 228 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia, a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q9EPC2
Til brug med (applikation) Functional Assay
Formulering protein with no preservative
Gen-id (Entrez) 64654
Molekylvægt (g/mol) 25.5 kDa
Navn Mouse FGF-23
Mængde 100 μg
Kilde E. coli
Regulatorisk status RUO
Endotoksin koncentration <1 EU/ μg
Gene Alias ADHR; FGF; Fgf23; FGF-23; FGFN; Fibroblast growth factor; Fibroblast growth factor 23; Fibroblast growth factor 23 C-terminal peptide; Fibroblast growth factor 23 N-terminal peptide; HPDR2; HYPF; Phosphatonin; PHPTC; tumor-derived hypophosphatemia inducing factor; Tumor-derived hypophosphatemia-inducing factor; UNQ3027/PRO9828
Fælles navn FGF23
Gen symbol FGF23
Biologisk aktivitet Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells. The expected ED50 for this effect is 0.3-0.5 ug/ml, in the presence of murine Klotho and heparin.
Konjugeret Unconjugated
Rekombinant Recombinant
Sekvens MYPDTSPLLG SNWGSLTHLY TATARTSYHL QIHRDGHVDG TPHQTIYSAL MITSEDAGSV VITGAMTRRF LCMDLHGNIF GSLHFSPENC KFRQWTLENG YDVYLSQKHH YLVSLGRAKR IFQPGTNPPP FSQFLARRNE VPLLHFYTVR PRRHTRSAED PPERDPLNVL KPRPRATPVP VSCSRELPSA EEGGPAASDP LGVLRRGRGD ARGGAGGADR CRPFPRFV
Indhold og opbevaring -20°C
Udtrykssystem E. coli
Form Lyophilized
Renhed eller kvalitetsklasse ≥ 95% by SDS-PAGE gel and HPLC analyses.
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