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R&D Systems™ Mouse DCC (NP_031857) VersaClone cDNA

Artikelnummer. 18796669
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10 μg
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18796669 10 μg
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Artikelnummer. 18796669 Leverandør R&D Systems™ Leverandørnr. RDC2719
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Beskrivelse

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

  • Also known as: Igdcc1; C030036D22Rik
  • DCC is a transmembrane protein that is a member of the immunoglobulin superfamily.
  • DCC is expressed on axons during development where its binding to Netrin-1 regulates axon migration and myelination. It inhibits apoptosis when bound by Netrin-1 and can induce apoptosis in the absence of ligand.
  • DCC also functions as an adhesion molecule and a tumor suppressor on intestinal epithelial cells.
  • Deficiencies in DCC function are associated with the development and metastasis of many tumors.
  • The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
  • For reasearch use only. Not for use in humans.
TRUSTED_SUSTAINABILITY

Tekniske data

Gene mDcc
Adgangsnummer NP_031857
Koncentration 10 μg at 0.2 μg/μL
Formulering cDNA is provided in 10 mM Tris-Cl, pH 8.5
Indsæt type 4357 bp
Gen-id (Entrez) 1630
Indhold og opbevaring Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Arter Mouse
Produktlinje R&D Systems
Mængde 10 μg
Produkttitel
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