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Motesanib Diphosphate, MedChemExpress

Artikelnummer. 16490107
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16490107 50 mg
16464796 100 mg
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Artikelnummer. 16490107 Leverandør Medchem Express Leverandørnr. HY10229

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Beskrivelse

MedChemExpress Motesanib Diphosphate (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret.

Motesanib Diphosphate (AMG 706 Diphosphate) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is approximately 10-fold more selective for VEGFR than PDGFR and Ret.

Tekniske data

Kemisk navn eller materiale Motesanib Diphosphate
CAS 857876-30-3
Farve White
Renhedsgrad noter Research
Molekylær formel C22H29N5O9P2
Mængde 50 mg
Synonym AMG 706 Diphosphate
Opløselighedsinformation DMSO : ≥ 110 mg/mL (193.17 mM) ∣H2O : 5 mg/mL (8.78 mM; ultrasonic and warming and heat to 60°C)
SMIL O=C(C1=CC=CN=C1NCC2=CC=NC=C2)NC3=CC(NCC4(C)C)=C4C=C3.O=P(O)(O)O.O=P(O)(O)O
Molekylvægt (g/mol) 569.44
Formel vægt 569.44
Procent renhed 99.64%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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