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Tocris Bioscience™ MOMBA
GREENER_CHOICE

Artikelnummer. 18765855
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Mængde:
250 mg
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Produktkod. Mængde
18765855 250 mg
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Beskrivning

Selective orthostatic agonist of hFFA2-DREADDs

MOMBA is a selective orthosteric agonist for human free fatty acid 2 (hFFA2) engineered receptors, designer receptors activated by designer drugs (DREADD), it shows no activity to wild-type hFFA2, hFFA3, and mouse FFA2. MOMBA inhibit forskolin-stimulated cAMP levels in cells expressing the hFFA2-DREADD receptor with improved potency and equivalent efficacy to Sorbic acid (Cat. No. 7119). In hFFA2-DREADD transgenic mice, MOMBA treatment significantly reduces gut transit and promotes concentration-dependent release of GLP-1 from colonic crypts. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifikationer

Kemisk navn eller materiale 4-Methoxy-3-methylbenzoic acid
CAS 6880-04-2
Mængde 250 mg
Mål DREADD Activators
Molekylær formel C9H10O3
Renhed 0.98
Produkttitel
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