missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ Cholera Toxin Subunit B (Recombinant), Alexa Fluor™ 555 Conjugate

Product Code. 11584247
500 μg, 500µg
Click to view available options
Quantity:
100 μg
500 μg
Unit Size:
100µg
500µg
This item is not returnable. View return policy
This item is not returnable. View return policy

Made from a recombinant version of the B subunit only to provide a very high-purity product that is completely free of the toxic A subunit

  • Cholera toxin B subunit (CT-B) attaches to cells by binding to ganglioside GM1, making it powerful tool for retrograde labeling of neurons
  • This tracer has been used in variety of applications, including tracing of rat forebrain afferents, projections of the parabrachial region, and neurons of the urinary bladder wall
  • When used in neuronal tracing applications, CT-B is typically introduced by pressure injection or by iontophoretic injection into neural tissue
  • At neutral pH, 11.4 kDa B subunit exists as 57 kDa pentamer
  • Lyophilized product can be dissolved in buffer (e.g., PBS) for use
  • More recently, researchers have found that CT-B can be used as marker for lipid rafts, which are membrane microdomains enriched in cholesterol and sphingolipids thought to be important in cell signaling
  • For lipid raft staining, cells are first incubated with fluorescent CT-B, then an anti-CT-B antibody is added to crosslink the CT-B in the lipid rafts into distinct patches on the plasma membrane
  • These patches are easily visualized by fluorescence microscopy

  • Label (Ex/Em): Alexa Fluor™ 555 (555/565nm)
  • At neutral pH, the 11.4 kDa B subunit exists as a 57 kDa pentamer

Cell Analysis, Cell Structure, Cell Tracing and Tracking, Cell Viability, Proliferation and Function, Cellular Imaging, Endocytosis, Exocytosis and Phagocytosis, Immunofluorescence (IF), Immunofluorescence Staining and Detection, Lipid Rafts, Microbial Tracking, Neuronal Tracing

Order Info

Shipping Condition: Room temperature

TRUSTED_SUSTAINABILITY

Specifications

Quantity 500 μg
Conjugate Alexa Fluor 555
Recombinant Recombinant
Content And Storage Store in freezer (-5 to -30°C) and protect from light.
Label Type Alexa Fluor Dyes
Shipping Condition Room Temperature
Protein Form Recombinant
Form Lyophilized
Protein Subtype Cholera Toxin
Product Line Alexa Fluor™

For Research Use Only. Not for use in diagnostic procedures.

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title
Invitrogen™ Cholera Toxin Subunit B (Recombinant), Alexa Fluor™ 555 Conjugate >

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.