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Tocris Bioscience™ (+)-MK 801 maleate

Beskrivelse
(+)-MK 801 maleate is a high affinity (Ki = 37.2 nM), selective and non-competitive NMDA receptor antagonist. (+)-MK 801 maleate acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux. It is an effective anti-ischemic agent in several animal models. (+)-MK 801 maleate increases motor activity in rat models. (+)-MK 801 maleate inhibits proliferation and increases apoptosis in hippocampal neural stem cells (NSCs). (+)-MK 801 maleate induces schizophrenia-like symptoms in rodents.
(-)-enantiomer also available.
Tekniske data
Tekniske data
| Kemisk navn eller materiale | (+)-MK 801 maleate |
| Mængde | 10 mg |
| Formel vægt | 337.37 |
| Renhed | >99% |
| Molekylvægt (g/mol) | 337.375 |
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