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MK-4101, MedChemExpress

Artikelnummer. 16499456
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Pakningsstørrelse:
100mg
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Artikelnummer. Mængde unitSize
16499456 50 mg -
16492758 10 mg -
16459995 2 mg -
16405507 5 mg -
16404226 100 mg 100mg
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Artikelnummer. 16499456 Leverandør Medchem Express Leverandørnr. HY100036

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Beskrivelse

MedChemExpress MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 μM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 μM for mouse cells; IC50 of 1 μM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis.

MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 μM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 μM for mouse cells

Tekniske data

Kemisk navn eller materiale MK-4101
Fysisk form Solid
CAS 935273-79-3
Farve White
Mængde 50 mg
Renhedsgrad noter Research
Molekylær formel C24H24F5N5O
Til brug med (applikation) Cancer-programmed cell death
Opløselighedsinformation DMSO : ≥ 50 mg/mL (101.32 mM)
SMIL FC(C1=CC=CC=C1C2=NN=C(C34CCC(C5=NOC(C6CC(F)(F)C6)=N5)(CC4)CC3)N2C)(F)F
Molekylvægt (g/mol) 493.47
Formel vægt 493.47
Procent renhed 98.1%
Grad Research
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