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Mitoxantrone, MedChemExpress

Artikelnummer. 16446206
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Artikelnummer. 16446206 Leverandør Medchem Express Leverandørnr. HY13502

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Beskrivelse

MedChemExpress Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity. Mitoxantrone also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.

Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity. Mitoxantrone also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.

Tekniske data

Kemisk navn eller materiale Mitoxantrone
CAS 65271-80-9
Farve Black
Renhedsgrad noter Research
Molekylær formel C22H28N4O6
Mængde 100 mg
Synonym Mitozantrone NSC 301739
Opløselighedsinformation DMSO : 62.5 mg/mL (140.61 mM; Need ultrasonic)
SMIL O=C1C2=C(C(NCCNCCO)=CC=C2NCCNCCO)C(C3=C(O)C=CC(O)=C13)=O
Molekylvægt (g/mol) 444.48
Formel vægt 444.48
Procent renhed 98.0%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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