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Mitoxantrone dihydrochloride, MedChemExpress

Artikelnummer. 16461877
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16461877 50 mg
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Artikelnummer. 16461877 Leverandør Medchem Express Leverandørnr. HY13502A

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Beskrivelse

MedChemExpress Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor.

Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively.

Tekniske data

Kemisk navn eller materiale Mitoxantrone dihydrochloride
CAS 70476-82-3
Farve Dark blue
Renhedsgrad noter Research
Molekylær formel C22H30Cl2N4O6
Mængde 50 mg
Synonym Mitozantrone dihydrochlorideNSC 301739 dihydrochloride
Opløselighedsinformation H2O : 100 mg/mL (193.27 mM; Need ultrasonic) ∣DMSO : ≥ 43 mg/mL (83.11 mM)
SMIL O=C1C2=C(C(NCCNCCO)=CC=C2NCCNCCO)C(C3=C(O)C=CC(O)=C13)=O.[H]Cl.[H]Cl
Molekylvægt (g/mol) 517.4
Formel vægt 517.4
Procent renhed 99.55%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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