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Tocris Bioscience™ Mirtazapine

Artikelnummer. 30001439
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30001439 10 mg
18035572 50 mg
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Artikelnummer. 30001439 Leverandør Tocris Bioscience™ Leverandørnr. 2018/10

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Description

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Mirtazapine is an antidepressant agent; potent 5-HT2, 5-HT3 and histamine H1 receptor antagonist and moderately potent α2-adrenoceptor antagonist (pKi values are 8.05, ∼ 8.1, 9.3 and 6.95 respectively). Enhances noradrenaline (NA) release in rat brain via inhibition of α2-adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pKi values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 85650-52-8
Molekylær formel C17H19N3

Specifications

Kemisk navn eller materiale Mirtazapine
Mængde 10 mg
Formel vægt 265.36
Renhed >99%
Molekylvægt (g/mol) 265.36
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