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Miransertib, MedChemExpress

Artikelnummer. 16483807
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Artikelnummer. 16483807 Leverandør Medchem Express Leverandørnr. HY19719

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Beskrivelse

MedChemExpress Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research. Miransertib is effective against Leishmania.

Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research. Miransertib is effective against Leishmania.

Tekniske data

Kemisk navn eller materiale Miransertib
CAS 1313881-70-7
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C27H24N6
Mængde 50 mg
Synonym ARQ-092
Opløselighedsinformation DMSO : 12.5 mg/mL (28.90 mM; Need ultrasonic)
SMIL NC1=NC=CC=C1C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(C6(N)CCC6)C=C5
Molekylvægt (g/mol) 432.52
Formel vægt 432.52
Procent renhed 96.28%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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