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Invitrogen™ MIF Recombinant Human Monoclonal Antibody (6E11)

Beskrivelse
MIF Recombinant Monoclonal Antibody for ICC/IF, Flow, ELISA
MIF (macrophage migration inhibitory factor) was one of the first cytokine activities to be discovered and was initially described as a T cell-derived factor that inhibits the random migration of macrophages (Weiser 1989). Recently, MIF was rediscovered as a pituitary hormone that act as the counterregulatory hormone for glucocorticoid action within the immune system (Bernhagen 1993, Mitchell 1995). MIF was released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secreted MIF counter-regulates the immunosuppressive effects of steroids on immune cell activation and cytokine production (Bucala 1998). MIF plays a critical role in the host control of inflammation and immunity.
Tekniske data
Tekniske data
| Antigen | MIF |
| Applikationer | ELISA, Flow Cytometry, Immunocytochemistry |
| Klassifikation | Recombinant Monoclonal |
| Klon | 6E11 |
| Koncentration | 1.77 mg/mL |
| Konjugeret | Unconjugated |
| Formulering | PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4 |
| Gene | Mif |
| Genadgangsnr. | P14174 |
| Gene Alias | cytokine; delayed early response protein 6; DER6; GIF; GLIF; glutathione-binding 13 kDa protein; Glycosylation-inhibiting factor; HGNC:7097; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MGC107654; Mif; MMIF; phenylpyruvate tautomerase |
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