missing translation for 'onlineSavingsMsg'
Få mere at vide
Få mere at vide
Invitrogen™ MICA/B Monoclonal Antibody (6D4), Biotin
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA538726
Denne vare kan ikke returneres.
Se returpolitik
Beskrivelse
This antibody recognizes a common extracellular epitope on MICA and MICB glycoproteins, transmembrane ligands of CD314 (NKG2D), and is able to block CD314-mediated activation of NK cells and cytotoxic T cells.
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells.
Tekniske data
| MICA/B | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 15 mM sodium azide; pH 7.4 | |
| Q29980, Q29983 | |
| MICA, MICB | |
| Transfected C1R cells expressing MICA. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Flow Cytometry, Immunoprecipitation, Immunocytochemistry | |
| 6D4 | |
| Biotin | |
| MICA | |
| HLA class I antigen; MHC class I chain-related protein A; MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence A; MHC class I polypeptide-related sequence B; MHC class I related sequence A; MHC class I-like molecule PERB11.2-IMX; MICA; MIC-A; MICB; MIC-B; PERB11.1; PERB11.2; sMICA; sMICB; soluble MICA; soluble MICB; stress inducible class I homolog; truncated MHC class I polypeptide-related sequence A | |
| Mouse | |
| Size-exclusion chromatography | |
| RUO | |
| 100507436, 4277 | |
| 4°C, do not freeze | |
| Liquid |
Korrektion af produktindhold
Dit input er vigtigt for os. Udfyld denne formular for at give feedback relateret til indholdet på dette produkt.
Produkttitel
Ser du en mulighed for forbedring?Del en indholdskorrektion