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Invitrogen™ MEP1B Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5112908
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Beskrivelse
MEP1B Polyclonal Antibody for Western Blot, IHC (P), ELISA
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
Especificaciones
| MEP1B | |
| Polyclonal | |
| Unconjugated | |
| Mep1b | |
| EC 3.4.24.63; Endopeptidase-2; MEP1B; Mep-1b; meprin 1 beta; meprin A; meprin A subunit beta; meprin A, beta; meprin B; meprin beta; N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta; PABA peptide hydrolase; PPH beta | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 17288, 4225 | |
| -20°C or -80°C if preferred | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 0.74 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q16820, Q61847 | |
| Mep1b | |
| Recombinant Human Meprin A subunit beta protein (480-652AA). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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