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Invitrogen™ MEK1/MEK2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA531917
Description
Recommended positive controls: 293T, NIH-3T3, JC. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (94%), Xenopus laevis (96%), Dog (100%), Pig (96%), Rabbit (100%), Chicken (98%), Rhesus Monkey (100%), Chimpanzee (98%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In brain, this pathway also plays a key role in synaptic (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
Specifications
MEK1/MEK2 | |
Polyclonal | |
Unconjugated | |
MAP2K2 | |
AA589381; CFC3; CFC4; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; EC 2.7.12.2; ERK activator kinase 1; ERK activator kinase 2; hypothetical protein; hypothetical protein LOC406728; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP kinase/Erk kinase 1; Map2k1; Map2k2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK1; MAPKK2; MEK 1; MEK 2; Mek1; MEK-1; Mek2; MEK-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase type 2; MK2; MKK1; MKK2; MP2K1; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen activated, kinase 2, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); si:ch211-242m18.2; wu:fj56a12; wu:fj61b01; zgc:56557; zgc:56557 protein | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
170851, 26395, 26396, 5604, 5605, 58960 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
P31938, P36506, P36507, Q01986, Q02750, Q63932 | |
MAP2K1, MAP2K2 | |
Recombinant fragment corresponding to a region within amino acids 1 and 300 of Human MEK1+2. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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