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Invitrogen™ Human MBL Oligomer ELISA Kit

Artikelnummer. 17883568
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Artikelnummer. 17883568 Leverandør Invitrogen™ Leverandørnr. BMS23292
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ELISA

The Human Mannose Binding Lectin (Hu MBL-2) ELISA quantitates Hu MBL-2 in human serum or plasma. The assay will exclusively recognize both natural and recombinant Hu MBL-2. Principle of the method The Human MBL-2 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen. Rigorous validation Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.

MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P11226
Analyseområde 0.05-40 ng/mL
Assay følsomhed 102 pg/mL
Konjugeret HRP
Immunoassay-kitformat Sandwich ELISA Kit
Produkttype ELISA
Protein familie Lectin
Prøvetype Plasma, Serum
Målarter Human
Til brug med (udstyr) Absorbance Microplate Reader
Gene Alias 27 kDa mannan-binding protein monomeric subunit; Ab2-001; Ab2-011; cMBl; COLEC1; collectin; Collectin1; collectin-1; c-type lectin; HSMBPC; L-MBP; mannan-binding lectin; mannan-binding lectin C; mannan-binding protein; mannose binding lectin (C); mannose binding lectin 2; mannose binding lectin 2 (protein C); mannose binding lectin, liver (A); mannose binding lectin, liver (C); mannose-binding lectin; mannose-binding lectin (protein C) 2; mannose-binding lectin (protein C) 2, soluble; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect); mannose-binding lectin C; mannose-binding lectin precursor protein; mannose-binding lectin-C; mannose-binding protein; Mannose-binding protein C; mannose-binding protein C (liver); mbl; MBL2; MBL2D; MBL-C; MBP; MBP1; MBPC; MBP-C; MBPD; MGC116832; MGC116833; pMBP-27; RA-reactive factor P28A subunit; ra-reactive factor polysaccharide-binding component p28A; RaRF p28A; RARF/P28A; serum protein; MBL; soluble mannose-binding lectin27 kDa mannan-binding protein monomeric subunit; Ab2-001; Ab2-011; cMBl; COLEC1; collectin; Collectin1; collectin-1; c-type lectin; HSMBPC; L-MBP; mannan-binding lectin; mannan-binding lectin C; mannan-binding protein; mannose binding lectin (C); mannose binding lectin 2; mannose binding lectin 2 (protein C); mannose binding lectin, liver (A); mannose binding lectin, liver (C); mannose-binding lectin; mannose-binding lectin (protein C) 2; mannose-binding lectin (protein C) 2, soluble; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect); mannose-binding lectin C; mannose-binding lectin precursor protein; mannose-binding lectin-C; mannose-binding protein; Mannose-binding protein C; mannose-binding protein C (liver); mbl; MBL2; MBL2D; MBL-C; MBP; MBP1; MBPC; MBP-C; MBPD; MGC116832; MGC116833; pMBP-27; RA-reactive factor P28A subunit; ra-reactive factor polysaccharide-binding component p28A; RaRF p28A; RARF/P28A; serum protein; MBL; soluble mannose-binding lectin; COLEC1; HSMBPC; MBL; MBL2; MBL2D; MBP; MBP-C; MBP1; MBPD
Gen-id (Entrez) 4153
Gen symbol MBL2
Interassay CV <10%
Intraassay CV <6%
Sættets indhold Pre-coated 96 well plate, Standard (2 vials), HRP Detection Antibody, Assay buffer Concentrate, Wash buffer concentrate, TMB, Stop solution, Adhesive Plate Covers
Etiket eller farvestof HRP
Protein aliaser Collectin-1, mannan-binding lectin, Mannan-binding protein, Mannose-binding lectin, mannose-binding lectin (protein C) 2, soluble (opsonic defect), mannose-binding lectin 2, Mannose-binding protein C, MBL2, MBP-C, MBP1
Mængde 96 Tests
Regulatorisk status RUO
Forsendelsestilstand Wet Ice
Opbevaringskrav 2-8°C
Mål MBL2
Test tid 1 hr 20 min
Samlet analysetid 3 hr 15 min
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