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Masitinib mesylate, MedChemExpress

Artikelnummer. 16470097
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Pakningsstørrelse:
100mg
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16403718 10 mg -
16400956 200 mg -
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Artikelnummer. 16470097 Leverandør Medchem Express Leverandørnr. HY10209A

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Beskrivelse

MedChemExpress Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity.

Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity.

Tekniske data

Kemisk navn eller materiale Masitinib mesylate
CAS 1048007-93-7
Farve White
Renhedsgrad noter Research
Molekylær formel C29H34N6O4S2
Mængde 50 mg
Synonym AB-1010 mesylate
Opløselighedsinformation DMSO : ≥ 30 mg/mL (50.44 mM)
SMIL O=C(NC1=CC=C(C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C)C4=CC=C(CN5CCN(CC5)C)C=C4.CS(=O)(O)=O
Molekylvægt (g/mol) 594.75
Formel vægt 594.75
Procent renhed 99.76%
Grad Research
Fysisk form Solid
Til brug med (applikation) Cancer-Kinase/protease
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Research purposes only

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