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Invitrogen™ Human MAPK8 (JNK1), His Tag Recombinant Protein

Artikelnummer. p-7076070
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Mængde:
10 μg
100 μg
Pakningsstørrelse:
100µg
10µg
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Artikelnummer. 15418453

Brand: Invitrogen™ PR5340A

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Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

MAPK8 (JNK1) is activated by the presence of misfolded proteins in the endoplasmic reticulum. It is also a crucial mediator of insulin resistance and obesity. It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P45983
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris with 2mM DTT, 0.05mM EDTA, 50% glycerol, 150mM NaCl, 0.05% Triton X-100 and no preservative; pH 7.5
Gen-id (Entrez) 5599
Molekylvægt (g/mol) 47.6 kDa
Navn Human MAPK8 (JNK1), His Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 100 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias AI849689; c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK; JNK1; JNK1 beta1 protein kinase; jnk1a-1; JNK1A2; JNK21B1/2; JNK3; JNK3A; JNK-46; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAPK 10; MAPK 8; MAPK10; Mapk8; mapk8 protein; mapk8b; MGC50974; mitogen activated protein kinase 8; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8b; MK10; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; Phospho-JNK; PRKM10; PRKM8; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1; SAPK1C; stress-activated protein kinase 1; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; zgc:112379
Fælles navn JNK1
Gen symbol MAPK8
KinaseFamily MAP Kinase Family
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag His-tag
Sekvens Full length
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser⁄Thr Kinases: CMGC Group
Forsendelsestilstand Dry Ice
Udtrykssystem Insect cells
Protein familie Kinases & Inhibitors
Protein form Recombinant, Full Length
Form Liquid
Forskningskategori Neurology, Oncology
Renhed eller kvalitetsklasse 95% by SDS-PAGE
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