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Invitrogen™ Human MAPK13 (p38 delta), His Tag Recombinant Protein

Artikelnummer. 11593487
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Mængde:
1 mg
10 μg
Pakningsstørrelse:
10µg
1mg
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Artikelnummer. 11593487

Brand: Invitrogen™ PV3656

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Beskrivelse

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

MAPK13 (p38 delta) is a serine/threonine kinase that transduces a variety of extracellular signals, including cytokine and environmental stress responses. MAPK13 also regulates the differentiation of keratinocytes. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer O15264
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris with 0.5mM EDTA, 150mM NaCl, 0.02% Triton X-100, 50% glycerol, 2mM DTT and no preservative; pH 7.5
Gen-id (Entrez) 5603
Molekylvægt (g/mol) 46.2 kDa
Navn Human MAPK13 (p38 delta), His Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 10 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias im:7136778; MAP kinase 13; MAP kinase p38 delta; MAPK 13; Mapk13; MAPK-13; mitogen activated protein kinase 13; mitogen-activated protein kinase 13; Mitogen-activated protein kinase p38 delta; p38 delta MAP kinase; p38delta; PRKM13; SAPK/Erk/kinase 4; SAPK4; Serk4; Stress-activated protein kinase 4
Fælles navn SAPK4
Gen symbol MAPK13
KinaseFamily MAP Kinase Family
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag His-tag
Sekvens Full length
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody)
Kinase Group Ser⁄Thr Kinases: CMGC Group
Forsendelsestilstand Dry Ice
Systemkompatibilitet LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate
Målindgang MAPK13
Target Gene mitogen-activated protein kinase 13
Udtrykssystem Baculovirus
Protein familie Kinases & Inhibitors
Protein form Recombinant, Full Length
Form Liquid
Protein undertype Serine/Threonine Kinases
Forskningskategori Signal Transduction
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