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MAP4K1 (HPK1) Recombinant Human Protein

MAP4K1 (HPK1) Recombinant Human Protein

Brand:  Invitrogen PV6356

Additional Details : Weight : 0.00001kg

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Product Code. 15402172

  • 8780.00 DKK / 100µg


Estimated Shipment date
from Supplier 28-11-2017
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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

MAP4K1 (also known as HPK1) or Hematopoietic progenitor kinase 1 is a hematopoietic cell-restricted member of the Ste20 serine/threonine kinase super family. MAP4K1 is a tissue-specific upstream activator of the MEKK/JNK/SAPK signaling pathway. MAP4K1 diminishes T cell receptor (TCR) signaling activity and T cell proliferation by phosphorylating the adaptor protein SLP-76. Recombinant human MAP4K1 (1-346) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use

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  • Specifications

    Specifications

    NP_009112.1
    Pharma and biopharma, protein assays and analysis, target and lead identification and validation
    MAP4K1 (HPK1) Recombinant Human Protein
    100μg
    For research use only. Not for use in diagnostic procedures
    MAP4K1
    MAP4K1 (HPK1) was pre-diluted in enzyme dilution buffer and assayed in 5mM MOPS (pH 7.2), 2.5mM β−glycerol-phosphate, 5mM MgCl2, 0.4mM EDTA, 1mM EGTA, 0.05mM DTT, with 50 μM ATP, trace [33P]-γ- ATP and 200μg/mL myelin basic protein (MBP) for 15 minutes at 30°C
    aa 1 to 346
    144nmoles of phosphate transferred to myelin basic protein (MBP) per minute per mg of total protein at 30°C
    GST Tag, His Tag
    0.1mg/mL
    65.0kDa
    >85% by SDS-PAGE
    –68 to –85°C
    1 Each
    MAP4K1 (HPK1) Recombinant Human Protein
    Kinase assay
    MAP4K1 (HPK1) Recombinant Human Protein
    Human
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