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Invitrogen™ Human MAP3K11 (MLK3), GST Tag Recombinant Protein

Artikelnummer. p-7121796
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Mængde:
10 μg
100 μg
Pakningsstørrelse:
100µg
10µg
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Artikelnummer. 12634770

Brand: Invitrogen™ PR6962A

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Beskrivelse

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length.

MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q16584
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris with 2mM DTT, 0.02% Triton X-100, 50% glycerol, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
Gen-id (Entrez) 4296
Molekylvægt (g/mol) 120.1 kDa
Navn Human MAP3K11 (MLK3), GST Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 100 μg
Kilde Human
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias 2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase
Fælles navn MLK3
Gen symbol MAP3K11
KinaseFamily MLK Kinase Family
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag GST-tag
Sekvens Full length
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser⁄Thr Kinases: TKL Group
Forsendelsestilstand Dry Ice
Udtrykssystem Insect cells
Protein familie Kinases & Inhibitors
Protein form Recombinant, Full Length
Form Liquid
Protein undertype Serine/Threonine Kinases
Forskningskategori Immunology, Oncology, Signal Transduction
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