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Invitrogen™ Human MAP2K5 (MEK5), GST Tag Recombinant Protein

Artikelnummer. p-7181503
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Mængde:
1 mg
10 μg
100 μg
Pakningsstørrelse:
10µg
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Artikelnummer. 15950303

Brand: Invitrogen™ A30977

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Beskrivelse

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This MAP2K5 (MEK5) recombinant human protein (full length) was expressed in insect cells. MAP2K5 (MEK5) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the LanthaScreen™ Eu Kinase Binding assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Full Length, Recombinant, Active The gene accession number for MAP2K5 (MEK5) is AAH08838.1.

MAP2K5 (MEK5) serine/threonine kinase (mitogen-activated protein kinase 5) or MEK5 is a dual specificity protein kinase that belongs to the MAP kinase family which specifically interacts with and activates MAPK7/ERK5. MAP2K5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MAP2K5 promoter may affect the risk of developing colorectal cancer (CRC).
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q13163
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering 50mM tris HCl with 0.1mM PMSF, 25% glycerol, 0.25mM DTT, 150mM NaCl, 0.1mM EDTA, 10mM glutathione and no preservative; pH 7.5
Gen-id (Entrez) 5607
Molekylvægt (g/mol) 76.4 kDa
Navn Human MAP2K5 (MEK5), GST Tag
pH-område 7.5
Oprensningsmetode Purified
Mængde 10 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias AI324775; AI428457; Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; Mkk5; PRKMK5
Fælles navn MEK5
Gen symbol MAP2K5
KinaseFamily MAP Kinases
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag GST-tag
Sekvens Full length
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Forsendelsestilstand Dry Ice
Udtrykssystem Insect cells
Protein familie Kinases & Inhibitors
Protein form Full Length, Recombinant, Active
Form Liquid
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