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STEMCELL Technologies LY294002

Artikelnummer. 17140032
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Mængde:
5 mg
25 mg
Pakningsstørrelse:
25mg
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17140032 5 mg -
17150032 25 mg 25mg
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Artikelnummer. 17140032 Leverandør STEMCELL Technologies Leverandørnr. 72152

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Beskrivelse

PI3K/AKT pathway inhibitor; Inhibits PI3K

  • LY294002 is a PI3K inhibitor that has greater potency and selectivity than quercetin, the structure on which it is based
  • LY294002 inhibits PI3K (IC50 = 1.4 μM) and also shows activity against CK2, but not PI4K, EGFR, PDGFR, MAPK, PKA, or PKC
  • (Davies et al.), Vlahos et al.)
  • Suppresses proliferation and self-renewal of mouse embryonic stem (ES) cells (Lianguzova et al.), Paling et al.)
  • Promotes differentiation to insulin-producing cells from mouse ES cells (Hori et al.)
  • Inhibits myotube formation from myoblasts (Coolican et al.), Jiang et al.)

Tekniske data

CAS 154447-36-6
Mængde 5 mg
Molekylær formel C19H17NO3
Renhed ≥98%
Produkttitel
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