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Tocris Bioscience™ LSN 3318839

Artikelnummer. 30226366
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5 mg
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30226366 5 mg
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Artikelnummer. 30226366 Leverandør Tocris Bioscience™ Leverandørnr. 7959/5

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Descrizione

Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator

LSN 3318839 is a potent glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator (EC50 = 14 nM). Acts as a molecular glue to stabilize peptide ligand and GLP1 receptor interaction. Potentiates activity of GLP-1 (7-36) (Cat. No. 2082) and the low-affinity metabolite GLP-1 (9-36) (Cat. No. 3266). LSN 3318839 alone or in combination with Sitagliptin (Cat. No. 6816) lowers glucose level in animal models of diabetes. LSN 3318839 is orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifica

Kemisk navn eller materiale (R)-2-(2-(1-((R)-1-(2,6-Dichloro-3-cyclopropylphenyl)ethyl)-1H-imidazo[4,5-c]pyridin-6-yl)phenyl)propanoic acid
CAS 2764704-18-7
Mængde 5 mg
Mål Glucagon-Like Peptide 1 Receptor Modulators
Molekylær formel C26H23Cl2N3O2
Renhed 0.98
Titolo del prodotto
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