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Invitrogen™ LRRK2 (WT) Recombinant Protein

Artikelnummer. 15383806
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Mængde:
1 mg
10 μg
100 μg
Pakningsstørrelse:
100µg
10µg
1mg
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Artikelnummer. 15383806

Brand: Invitrogen™ A15197

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Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This full-length, purified and active wild-type LRRK2 protein may be useful in research to better understand the native protein, unaffected by mutations, as well as to explore the mechanisms underlying the disease. Increase disease relevance by interrogating a purified and active full-length LRRK2 protein Uncover novel compounds or hits specific to the full-length form Advance Parkinson's research using the full-length protein and validated assays Related Links:LRRK2 Tools for Advancing Parkinson's Disease ResearchLanthaScreen™ Kinase Activity AssayLanthaScreen™ Eu Kinase Binding Assay Protein Form: Recombinant, Full Length.

LRRK2 (Leucine Rich Repeat Kinase 2) is a Protein Coding gene. Diseases associated with LRRK2 include Parkinson Disease 8, Autosomal Dominant and Hereditary Late-Onset Parkinson Disease. Among its related pathways are Signaling by PTK6 and ncRNAs involved in Wnt signaling in hepatocellular carcinoma. Gene Ontology (GO) annotations related to LRRK2 (G2019S Mutant) include protein homodimerization activity and transferase activity, transferring phosphorus-containing groups. An important paralog of LRRK2 (G2019S Mutant) is TNNI3K. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q5S007
Koncentration See Label
Til brug med (applikation) Kinase Assay
Formulering Proprietary buffer with no preservative
Gen-id (Entrez) 120892
Molekylvægt (g/mol) 288 kDa
Navn LRRK2 (WT)
Oprensningsmetode Purified
Mængde 10 μg
Opbevaringskrav -80°C, Avoid Freeze/Thaw Cycles
Regulatorisk status RUO
Gene Alias LRRK2
Fælles navn LRRK2 (WT)
Gen symbol LRRK2
KinaseFamily LRRK Kinase Family
Produkttype Protein
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag DYKDDDDK-tag
Sekvens Full length
Indhold og opbevaring -80°C, Avoid Freeze/Thaw Cycles
Udtrykssystem Baculovirus
Protein familie Kinases & Inhibitors
Protein form Recombinant, Full Length
Form Liquid
Forskningskategori Neurobiology
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