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Invitrogen™ LMTK3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5114265
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Beskrivelse
Immunogen sequence: RGLLKSPRAA DEPEDSELER KRKMVSFHGD VTVYLFDQET PTNELSVQGT For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 93%; Pig: 100%.
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. [UniProt].
Tekniske data
| LMTK3 | |
| Polyclonal | |
| Unconjugated | |
| LMTK3 | |
| Aatyk3; Apoptosis-associated tyrosine kinase 3; BC059845; KIAA1883; Lemur tyrosine kinase 3; LMR3; Lmtk3; LOC691056; PPP1R101; protein phosphatase 1, regulatory subunit 101; serine/threonine-protein kinase LMTK3; similar to 5E5 antigen; TYKLM3 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 381983 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| Q5XJV6 | |
| LMTK3 | |
| Synthetic peptide directed towards the middle region of Mouse Lmtk3. | |
| 100 μL | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
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