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Tocris Bioscience™ Lestaurtinib
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Product Code. 18045682
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1 mg
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18045682 1 mg
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Product Code. 18045682 Supplier Tocris Bioscience™ Supplier No. 3395/1

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Description

JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB

Potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3 and < 25 nM, respectively). Also inhibits Aurora kinase A and B (IC50 values are 8.1 and 2.3 nM, respectively) and prevents STAT5 phosphorylation (IC50 = 20 - 30 nM). Exhibits antiproliferative activity in vitro (IC50 = 30 - 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disorders in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Kemisk navn eller materiale Lestaurtinib
CAS 111358-88-4
Mængde 1 mg
Molekylær formel C26H21N3O4
Formel vægt 439.46
Renhed >99%
Molekylvægt (g/mol) 439.47
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