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Lck Inhibitor, MedChemExpress

Artikelnummer. 16477707
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Artikelnummer. Mængde
16477707 5 mg
16445746 100 mg
16434978 10 mg
16401227 50 mg
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Artikelnummer. 16477707 Leverandør Medchem Express Leverandørnr. HY12072

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Beskrivelse

MedChemExpress Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC50s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis.

Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC50s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis.

Tekniske data

Kemisk navn eller materiale Lck Inhibitor
CAS 847950-09-8
Farve Yellow
Renhedsgrad noter Research
Molekylær formel C31H30N8O
Mængde 5 mg
Opløselighedsinformation DMSO : 100 mg/mL (188.46 mM; Need ultrasonic)
SMIL O=C1N(C2=C(C)C=CC=C2C)C3=NC4=CC=CC=C4N3C5=NC(NC6=CC=C(N7CCN(C)CC7)C=C6)=NC=C15
Molekylvægt (g/mol) 530.62
Formel vægt 530.62
Procent renhed 98.2%
Grad Research
Fysisk form Solid
Til brug med (applikation) COVID-19-immunoregulation
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Research purposes only

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