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Invitrogen™ LanthaScreen™ Tb-peIF2a (pSer52) Antibody
The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis.
Brand: Invitrogen™ PV4816
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Beskrivelse
The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.
For use in combination with the GFP-EIF2alpha physiological protein substrate (Cat. No. PV4809) to evaluate inhibitors in medium to high throughput screening applications.
Tekniske data
| Serine/threonine kinase | |
| 0.47mg/mL | |
| 150kDa | |
| RUO | |
| Primary | |
| Terbium-labeled peIF2a (pThr46) antibody in HEPES buffered saline. Store at -20°C. | |
| 340/490, 520 nm | |
| Dry Ice | |
| Hu | |
| LanthaScreen |
| Kinase Assay | |
| Tb (Terbium)/Lanthanide Chelates | |
| 1 mg | |
| Pharma and Biopharma | |
| 1 Each | |
| Liquid | |
| Human | |
| End Point | |
| Ser/Thr Kinases |
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Produkttitel
For Research Use Only. Not for use in diagnostic procedures.
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