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Tocris Bioscience™ Lactacystin
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Artikelnummer. 30001297
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Mængde:
200 μg
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Artikelnummer. Mængde
30001297 200 μg
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Artikelnummer. 30001297 Leverandør Tocris Bioscience™ Leverandørnr. 2267/200U

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Beskrivelse

Cell-permeable, potent and selective proteasome inhibitor

A cell-permeable, potent and selective proteasome inhibitor. A Streptomyces metabolite that is thought to bind irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like activities. Induces neurite outgrowth in Neuro 2a neuroblastoma cells and has been reported to induce apoptosis in human monoblast U937 cells. Also inhibits NF-κB activation (IC50 = 10 μM).
TRUSTED_SUSTAINABILITY

Specifications

Kemisk navn eller materiale Lactacystin
CAS 133343-34-7
Mængde 200 μg
Molekylær formel C15H24N2O7S
Formel vægt 376.42
Renhed >98%
Molekylvægt (g/mol) 376.424
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