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Estrogen Receptor (SP1) Rabbit Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunohistochemistry and western blotting experiments with Epredia™ Estrogen Receptor (SP1), Rabbit Monoclonal Antibody.
Brand: Epredia RM-9101-R7
Additional Details : Weight : 4.98950kg
Description
Recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, and is translated into a protein with six functionally discrete domains, labeled A through F. This antibody strongly stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.Host Species: Rabbit
Clone: SP1
Isotype: IgG
Species Reactivity: Human, Mouse and Hamster. Others not tested.
Epitope: C-terminus
Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor
Molecular Weight: 67 kDa
Positive Control: Breast CA, MCF-7 cells
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence (Not verified)
- Flow Cytometery (Not verified)
Specifications
| Estrogen Receptor (SP1) | |
| Monoclonal | |
| Unconjugated | |
| Synthetic peptide derived from C-terminal of human estrogen receptor | |
| IVD | |
| Primary | |
| Prediluted |
| Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| SP1 | |
| Rabbit | |
| 7 mL | |
| Steroids Hormones and Growth Factors | |
| Hamster, Human, Mouse | |
| IgG |