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Tocris Bioscience™ Ko 143
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Product Code. 18004752
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18004752 1 mg
30001334 10 mg
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Product Code. 18004752 Supplier Tocris Bioscience™ Supplier No. 3241/1

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Description

Potent and selective BCRP inhibitor

Potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC90 = 26 nM). Displays > 200-fold selectivity over P-gp and MRP-1 transporters. Increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance. Inhibits ABCB1 and ABCC1 at higher concentrations. Rapidly metabolized in rat plasma.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 461054-93-3
Molekylær formel C26H35N3O5

Specifications

Kemisk navn eller materiale Ko 143
Mængde 1 mg
Formel vægt 469.57
Renhed >99%
Molekylvægt (g/mol) 469.58
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