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Invitrogen™ KLF4 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA523184

Produktkode 13227748

  • 4280.00 DKK / 100µg

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Beskrivelse

Beskrivelse

The amino acid sequence used as immunogen for the antibody is 100% homologous in human and chimpanzee.

Kruppel like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to a family of conserved Kruppel-like factor family of DNA binding zinc finger transcription factors. KLF4 exerts its functional relevance across varied cellular pathways. As one of the four Yamanaka factors, it plays a key role in reprogramming differentiated cells into pluripotent stem cells. Most studies have focused on its specific role in endothelial cell signaling, adipogenesis, differentiation, embryogenesis and cell cycle control. Localization plays an important role in the biological significance of this protein wherein nuclear localization is associated with its function as an oncogene and cytosolic localization with tumor suppression specific effect.
TRUSTED_SUSTAINABILITY
Tekniske data

Tekniske data

KLF4
Polyclonal
Unconjugated
KLF4
endothelial Kruppel-like zinc finger protein; epithelial zinc finger protein EZF; Ezf; Gklf; gut Kruppel-like factor; gut-enriched krueppel-like factor; high mobility group nucleosomal binding domain 3; high mobility group nucleosome-binding domain-containing protein 3; HMGN3; KLF4; Krueppel-like factor 4; Kruppel like factor 4; Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); Kruppel-like factor 4 (gut); PNAS-24; PNAS-25; RP11-150J11.1; thyroid hormone receptor interacting protein 7; Thyroid receptor-interacting protein 7; TR-interacting protein 7; TRIP7; Zie
Rabbit
Protein G
RUO
114505, 16600, 9314
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.05% sodium azide
O43474, Q60793
KLF4
A portion of amino acids 1-50 of human KLF4.
100 μg
Primary
Human, Mouse, Rat, Monkey
Antibody
IgG
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