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KIT [V654A] Recombinant Human Protein

KIT [V654A] Recombinant Human Protein

Brand:  Invitrogen PR7738A

Additional Details : Weight : 0.01000kg

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Product Code. 15408623

  • 9370.00 DKK / 100µg


Estimated Shipment date
from Supplier 28-09-2017
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Disclaimers:

For Research Use Only. Not for use in diagnostic procedures.


Description

Description

KIT is a proto-oncogene encoding a transmembrane tyrosine kinase receptor for stem cell factor required for normal hematopoiesis, melangenesis and gametogenesis. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. The clinically observed V654A mutant has been demonstrated to be resistant to inhibition with imatinib.
Specifications

Specifications

NP_000213, V654A
Protein assays and analysis
Frozen
KIT [V654A] Recombinant Human Protein
100μg
For research use only. Not for use in diagnostic procedures
KIT V654A
KIT V654A was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP, 200μg/mL poly [Glu, Tyr] 4:1 substrate and trace [32P]-γ-ATP for 10 minutes at 30°C
Baculovirus
Amino acids 544-976
5nmoles of phosphate transferred to poly [Glu, Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 20μg/mL
His Tag
0.46mg/mL
Frozen
53.2kDa
50% by SDS-PAGE
–80°C
1 Each
KIT [V654A] Recombinant Human Protein
Kinase assay
PDGFR
KIT [V654A] Recombinant Human Protein
Human