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Invitrogen™ Human KIT [V559D], GST Tag Recombinant Protein Product Code.: 17148775
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Invitrogen™ Human KIT [V559D], GST Tag Recombinant Protein

Product Code. 17148775
1 mg, 1mg
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Quantity:
1 mg
10 ÎĽg
100 ÎĽg
Unit Size:
100µg
10µg
1mg
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Product Code. 17148775

Brand: Invitrogen™ A33356

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Description

Recombinant Protein

KIT receptor tyrosine kinase is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P10721
Concentration See Label
For Use With (Application) Kinase Assay
Format Kit
Formulation 50 mM tris HCl with 0.1 mM EDTA, 0.1 mM PMSF, 0.25 mM DTT, 10 mM glutathione, 150 mM NaCl, 25% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 3815
Molecular Weight (g/mol) 75.3 kDa
Name Human KIT [V559D], GST Tag
Quantity 1 mg
Gene Alias KIT
Common Name KIT (V559D Mutant)
KinaseFamily PDGFR Kinase Family
Protein Length 544-end
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Shipping Condition Dry Ice
Expression System Insect cells
Protein Form Recombinant, Active, Catalytic, Mutant
Form Liquid
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