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Ki16425, MedChemExpress

Artikelnummer. 16475618
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Mængde:
5 mg
10 mg
50 mg
Pakningsstørrelse:
5mg
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16475618 10 mg -
16438317 5 mg 5mg
16461787 50 mg -
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Artikelnummer. 16475618 Leverandør Medchem Express Leverandørnr. HY13285

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Beskrivelse

MedChemExpress Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells.

Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells.

Tekniske data

Kemisk navn eller materiale Ki16425
Fysisk form Solid
CAS 355025-24-0
Farve Off-White
Mængde 10 mg
Renhedsgrad noter Research
Molekylær formel C23H23ClN2O5S
Til brug med (applikation) Cancer-Kinase/protease
Synonym Debio 0719
Opløselighedsinformation DMSO : ≥ 100 mg/mL (210.54 mM)
SMIL ClC1=C(C=CC=C1)C(C)OC(NC2=C(ON=C2C)C3=CC=C(C=C3)CSCCC(O)=O)=O
Molekylvægt (g/mol) 474.96
Formel vægt 474.96
Procent renhed 98.11%
Grad Research
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Research purposes only

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