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Kartogenin, MedChemExpress

Artikelnummer. 16499557
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Artikelnummer. 16499557 Leverandør Medchem Express Leverandørnr. HY16268

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Beskrivelse

MedChemExpress Kartogenin (KGN) is an inducer of differentiation of human mesenchymal stem cells into chondrocytes, with an EC50 of 100 nM. Kartogenin binds filamin A, disrupts its interaction with the transcription factor core-binding factor β subunit (CBFβ), and induces chondrogenesis by regulating the CBFβ-RUNX1 transcriptional program. Kartogenin can be used for the research of osteoarthritis (OA).

Kartogenin (KGN) is an inducer of differentiation of human mesenchymal stem cells into chondrocytes, with an EC50 of 100 nM. Kartogenin binds filamin A, disrupts its interaction with the transcription factor core-binding factor β subunit (CBFβ), and induces chondrogenesis by regulating the CBFβ-RUNX1 transcriptional program. Kartogenin can be used for the research of osteoarthritis (OA).

Tekniske data

Kemisk navn eller materiale Kartogenin
Fysisk form Powder
CAS 4727-31-5
Farve Off-White
Mængde 5 mg
Renhedsgrad noter Research
Molekylær formel C20H15NO3
Synonym KGN
Opløselighedsinformation DMSO : ≥ 42 mg/mL (132.35 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMIL O=C(O)C1=CC=CC=C1C(NC2=CC=C(C3=CC=CC=C3)C=C2)=O
Molekylvægt (g/mol) 317.34
Formel vægt 317.34
Procent renhed 95.0%
Grad Research
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Research purposes only

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