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Kanamycin sulfate from Streptomyces kanamycetikus, MP Biomedicals™

Artikelnummer. 11491175 Shop alle MP Biomedicals produkter
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Product Code. 11491175 Supplier MP Biomedicals Supplier No. 0219985325

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Kanamycin sulfate from Streptomyces kanamycetikus USP Grade, White Powder

  • It is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus.
  • It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium.
  • Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene.
  • Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma.
  • It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding.
  • Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and partial cross-resistance has been reported between kanamycin and streptomycin. Aminoglycosidemodifying enzymes (acetyltransferase, phosphotransferase, nucleotidyltransferase) alter the antibiotic, preventing its interaction with ribosomes.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 25389-94-0
Molekylær formel C18H38N4O15S
Molekylvægt (g/mol) 582.58
MDL nummer MFCD00070253
InChI nøgle OOYGSFOGFJDDHP-KMCOLRRFSA-N
Synonym Kanamycin A, Kanamycin sulfate salt

Specifications

Fysisk form Pulver
pH 6.5 to 8.5 (1% solution)
Smeltepunkt >250°C
Tab ved tørring <4%
Styrke >750 µg/mg
Farve Hvid
Mængde 25 g
Opløselighedsinformation Soluble in 10-50mg/mL of Water
Grad USP
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