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Tocris Bioscience™ Kainic acid (synthetic)

Artikelnummer. 18034912
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Artikelnummer. Mængde
18034912 1 mg
18777646 10 mg
18717446 50 mg
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Artikelnummer. 18034912 Leverandør Tocris Bioscience™ Leverandørnr. 7065/1

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Beskrivelse

Kainate agonist; excitant and neurotoxin

Kainic acid, also known as kainate, is a selective agonist of kainate ionotropic glutamate receptors (EC50 = 0.6 μM to 7.4 μM) and a partial agonist at AMPA receptors (EC50 = 31 μM to 170 μM). Kainic acid is used to model epilepsy in vivo and to study the mechanisms of neurodegeneration and neurocytosis induced by excess stimulation by kainic acid. Kainate is shown to be involved in amyloidogenic processing of amyloid precursor protein and Aβ peptides in Alzheimers. Synthetic version of Kainic acid (Cat. No. 0222) Related compounds include the kainate receptor agonist Domoic acid (Cat. No. 0269) and the antagonist NBQX (Cat. No. 0373).
TRUSTED_SUSTAINABILITY

Tekniske data

Kemisk navn eller materiale (2 S,3 S,4 S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
CAS 487-79-6
Mængde 1 mg
Molekylær formel C10H15NO4
Renhed 98%
Produkttitel
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