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JW 55, Tocris Bioscience™

Artikelnummer. 18074732
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Artikelnummer. Mængde
18074732 10 mg
18045522 50 mg
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Artikelnummer. 18074732 Leverandør Tocris Bioscience Leverandørnr. 4514/10

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Beskrivelse

Tankyrase inhibitor

Inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2). Activity results in stabilization of Axin2 and increased degradation of β-catenin; inhibits the β-catenin signaling pathway. Also shown to decrease canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines; reduces cell cycle progression and proliferation in SW480 cells in vitro.
TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 664993-53-7
Molekylær formel C25H26N2O5
Molekylvægt (g/mol) 434.49
MDL nummer MFCD03863265
InChI nøgle ZJZWZIXSGNFWQQ-UHFFFAOYSA-N
Synonym n-4-4-4-methoxyphenyl oxan-4-yl methylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl carbamoyl phenyl furan-2-carboxamide, qcr-64, n-4-4-4-methoxyphenyl oxan-4-yl methyl carbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-ylmethylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methylcarbamoyl phenyl furan-2-carboxamide, n-4-4-4-methoxyphenyl tetrahydro-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furamide, n-4-tetrahydro-4-4-methoxyphenyl-2h-pyran-4-yl methyl amino carbonyl phenyl-2-furancarboxamide
PubChem CID 2946601
IUPAC navn N-[4-({[4-(4-methoxyphenyl)oxan-4-yl]methyl}carbamoyl)phenyl]furan-2-carboxamide
SMIL COC1=CC=C(C=C1)C1(CNC(=O)C2=CC=C(NC(=O)C3=CC=CO3)C=C2)CCOCC1

Tekniske data

Kemisk navn eller materiale JW 55
Mængde 10 mg
Formel vægt 434.48
Procent renhed >98%
Produkttitel
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