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JNJ-39758979, MedChemExpress

Artikelnummer. 16466017
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Artikelnummer. 16466017 Leverandør Medchem Express Leverandørnr. HY101189

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MedChemExpress JNJ-39758979 is a selective, orally active, and high-affinity histamine H4 receptor antagonist with Kis of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively. JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. JNJ-39758979 shows good anti-inflammatory and antipruritic activity.

JNJ-39758979 is a selective, orally active, and high-affinity histamine H4 receptor antagonist with Kis of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively. JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. JNJ-39758979 shows good anti-inflammatory and antipruritic activity.

Tekniske data

Kemisk navn eller materiale JNJ-39758979
Fysisk form Solid
CAS 1046447-90-8
Farve White
Mængde 5 mg
Renhedsgrad noter Research
Molekylær formel C11H19N5
Til brug med (applikation) Neuroscience-Neuromodulation
Opløselighedsinformation DMSO : 33.33 mg/mL (150.61 mM; Need ultrasonic)
SMIL NC1=NC(C(C)C)=CC(N2C[C@H](N)CC2)=N1
Molekylvægt (g/mol) 221.3
Formel vægt 221.3
Procent renhed 98.0%
Grad Research
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Research purposes only

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