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Ivosidenib, MedChemExpress

Artikelnummer. 16497618
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Artikelnummer. Mængde
16497618 10 mg
16490088 5 mg
16453637 50 mg
16437536 100 mg
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Artikelnummer. 16497618 Leverandør Medchem Express Leverandørnr. HY18767

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Beskrivelse

MedChemExpress Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity.

Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity.

Tekniske data

Kemisk navn eller materiale Ivosidenib
CAS 1448347-49-6
Farve White
Renhedsgrad noter Research
Molekylær formel C28H22ClF3N6O3
Mængde 10 mg
Synonym AG-120
Opløselighedsinformation DMSO : ≥ 39 mg/mL (66.90 mM)
SMIL ClC1=C([C@H](N(C2=CC(F)=CN=C2)C([C@H]3N(C4=NC=CC(C#N)=C4)C(CC3)=O)=O)C(NC5CC(F)(F)C5)=O)C=CC=C1
Molekylvægt (g/mol) 582.96
Formel vægt 582.96
Procent renhed 98.01%
Grad Research
Fysisk form Powder
Til brug med (applikation) Cancer-programmed cell death
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Research purposes only

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