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Itraconazole, MedChemExpress

Artikelnummer. 16407356
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Mængde:
100 mg
500 mg
Pakningsstørrelse:
500mg
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16407356 100 mg -
16461876 500 mg 500mg
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Artikelnummer. 16407356 Leverandør Medchem Express Leverandørnr. HY17514100mg

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Beskrivelse

MedChemExpress Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ∼800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.

Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ∼800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.

Tekniske data

Kemisk navn eller materiale Itraconazole
Fysisk form Solid
CAS 84625-61-6
Farve White
Mængde 100 mg
Renhedsgrad noter Research
Molekylær formel C35H38Cl2N8O4
Til brug med (applikation) COVID-19-immunoregulation
Synonym R51211
Opløselighedsinformation DMSO : 6.25 mg/mL (8.86 mM; Need ultrasonic)
SMIL ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6C(C)CC)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7
Molekylvægt (g/mol) 705.63
Formel vægt 705.63
Procent renhed 99.15%
Grad Research
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Research purposes only

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