missing translation for 'onlineSavingsMsg'
Få mere at vide
  1. Home
  2. Products
  3. Proteinanalysereagenser
  4. Bioaktive små molekyler
  5. STEMCELL Technologies IQ-1

STEMCELL Technologies IQ-1

Artikelnummer. 17140122
Encompass_Preferred
Skift visning
Klik for at se tilgængelige muligheder
Mængde:
5 mg
Pakningsstørrelse:
5mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Artikelnummer. Mængde unitSize
17140122 5 mg 5mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denne vare kan ikke returneres. Se returpolicy
Artikelnummer. 17140122 Leverandør STEMCELL Technologies Leverandørnr. 72772

Please to purchase this item. Need a web account? Register with us today!

Denne vare kan ikke returneres. Se returpolicy

Beskrivelse

WNT pathway activator; Inhibits protein phosphatase PP2A

  • IQ-1 selectively inhibits p300-dependent β-catenin signaling by binding to the PR72/130 subunit of protein phosphatase PP2A, leading to decreased phosphorylation of the β-catenin coactivator, p300, and decreased affinity of p300 for β-catenin
  • IQ-1 thereby inhibits β-catenin/p300 interaction while increasing β-catenin/CBP mediated transcription (Miyabayashi et al.)
  • Used with Wnt3a to maintain pluripotency of mouse embryonic stem (ES) cells in the absence of mouse embryonic fibroblasts (MEFs), serum, or exogenous leukemia inhibitory factor (LIF; Miyabayashi et al.)
  • Enhances expansion of mouse ES-derived cardiovascular progenitor cells (Schenke-Layland et al.)
  • Induces the conversion of cancer cells to a side population of cancer stem-like cells with high levels of drug resistance and tumorigenicity (He et al.)

Tekniske data

CAS 331001-62-8
Mængde 5 mg
Molekylær formel C21H22N4O2
Renhed ≥98%
Produkttitel
Vælg et problem

Ved at klikke på Send, anerkender du, at du kan blive kontaktet af Fisher Scientific med hensyn til den feedback, du har givet i denne formular. Vi deler ikke dine oplysninger til andre formål. Alle angivne kontaktoplysninger skal også vedligeholdes i overensstemmelse med vores Privatlivspolitik.