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DiscoverX InCELL Hunter™ HEK 293 BLK Kinase Binding Cell Line
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Mængde:
2 hætteglas
Beskrivelse
The InCELL Hunter™ HEK 293 BLK Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of BLK via detection of BLK levels. This product uses EFC technology. The cell line included overexpresses BLK target protein fused to PL. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.
Tekniske data
Tekniske data
| Assay Entry | Target Engagement |
| Cellelinje | 293H |
| Til brug med (applikation) | Cell Lines |
| Mængde | 2 hætteglas |
| Målindgang | BLK |
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Produkttitel
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