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Imatinib, MedChemExpress

Artikelnummer. 16481519
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5 g
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Artikelnummer. Mængde
16481519 1 g
16441776 500 mg
16431186 200 mg
16459127 5 g
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Artikelnummer. 16481519 Leverandør Medchem Express Leverandørnr. HY15463

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Beskrivelse

MedChemExpress Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV.

Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV.

Tekniske data

Kemisk navn eller materiale Imatinib
Fysisk form Solid
CAS 152459-95-5
Farve Light Yellow
Mængde 1 g
Renhedsgrad noter Research
Molekylær formel C29H31N7O
Til brug med (applikation) Cancer-Kinase/protease
Synonym STI571 CGP-57148B
Opløselighedsinformation DMSO : 12.5 mg/mL (25.32 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
SMIL CN(CC1)CCN1CC2=CC=C(C(NC3=CC=C(C)C(NC4=NC(C5=CC=CN=C5)=CC=N4)=C3)=O)C=C2
Molekylvægt (g/mol) 493.6
Formel vægt 493.6
Procent renhed 99.4%
Grad Research
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Research purposes only

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