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Proteintech HumanKine™ recombinant human IL-12 beta protein
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Mængde:
10 μg
100 μg
1000 μg
Beskrivelse
IL-12p40, also known as IL-12B, is a subunit of both the IL-12 and IL-23 cytokines. It is not thought to be bioactive on its own, but it has been shown to regulate IL-12 activity in antagonistic manner by competitively binding with the IL-12 receptor. IL-12p40 also functions as a chemoattractant molecule for macrophage infiltration into tumor sites. There has additionally been evidence to suggest that IL-12p40 mediates a protective immune response against mycobacterial infection by serving as a necessary component for granuloma formation and promoting Th1 effector cell functions (PMID: 17126601, 10453037, 11739515).
Tekniske data
Tekniske data
| Adgangsnummer | P29460 |
| Formulering | 1 x PBS pH 7.4 |
| Gen-id (Entrez) | 3593 |
| Molekylvægt (g/mol) | 37-50 kDa |
| Mængde | 10 μg |
| Kilde | HEK293 |
| Opbevaringskrav | Lyophilized product should be stored at -20°C to -80°C until expiry date and (at Room Temperature for 2 weeks.) |
| Endotoksin koncentration | <0.1 EU/μg |
| Specifik reaktivitet | Human |
| Rekombinant | Recombinant |
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