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Invitrogen™ Human ZIP13 (aa 42-67) Control Fragment Recombinant Protein

Artikelnummer. 30182694
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Mængde:
100 μL
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Artikelnummer. 30182694

Brand: Invitrogen™ RP99870

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Beskrivelse

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60566 (PA5-60566. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer Q96H72
Koncentration ≥5.0 mg/mL
Til brug med (applikation) Blocking Assay, Control
Formulering 1 M urea, PBS with no preservative; pH 7.4
Gen-id (Entrez) 91252
Navn Human ZIP13 (aa 42-67) Control Fragment
Mængde 100 μL
Regulatorisk status RUO
Gene Alias LIV-1 subfamily of ZIP zinc transporter 9; LZT-Hs9; SLC39A13; solute carrier family 39 (metal ion transporter), member 13; solute carrier family 39 (zinc transporter), member 13; solute carrier family 39 member 13; Zinc transporter ZIP13; ZIP13; ZIP-13; Zrt- and Irt-like protein 13
Fælles navn ZIP13
Gen symbol SLC39A13
Konjugeret Unconjugated
Arter Human
Rekombinant Recombinant
Protein tag His-ABP-tag
Sekvens TATACRLDNKESESWGALLSGERLDT
Indhold og opbevaring -20°C, Avoid Freeze/Thaw Cycles
Udtrykssystem E. coli
Form Liquid
Renhed eller kvalitetsklasse >80% by SDS-PAGE and Coomassie blue staining
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