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Invitrogen™ Human TIMP1 Recombinant Protein

Artikelnummer. 11549051
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Mængde:
1 mg
Pakningsstørrelse:
1mg
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Artikelnummer. 11549051

Brand: Invitrogen™ RP75735

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Beskrivelse

Recombinant Protein

This product contains a purified 184 amino acid fragment (aa24-207) corresponding to the mature TIMP-1 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1.
TRUSTED_SUSTAINABILITY

Tekniske data

Adgangsnummer P01033
Koncentration 0.29 mg/mL
Til brug med (applikation) Control, Western Blot
Formulering 25 mM sodium acetate with 50% glycerol and no preservative; pH 4.8
Gen-id (Entrez) 7076
Molekylvægt (g/mol) 25.21 kDa
Navn Human TIMP1
pH-område 4.8
Mængde 1 mg
Kilde E. coli
Immunogen N/A
Regulatorisk status RUO
Gene Alias CLGI; collagenase inhibitor; Collagenase inhibitor 16C8 fibroblast; EG-1; Embryogenin-1; EPA; EPO; erythroid potentiating activity; erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; HCI; Metalloproteinase inhibitor; metalloproteinase inhibitor 1; metalloproteinase tissue inhibitor; metalloproteinase tissue inhibitor 1; MMP inhibitor; RP1-230G1.3; Timp; TIMP 1; TIMP metallopeptidase inhibitor 1; TIMP1; TIMP-1; TIMP-1 protein; tissue inhibitor of matrix metalloproteinase-1; tissue inhibitor of metal proteinases; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor); tissue inhibitor of metalloproteinase-1; tissue inhibitor of metalloproteinases; tissue inhibitor of metalloproteinases 1; TPA-induced protein; TPA-S1
Fælles navn TIMP1
Gen symbol TIMP1
Konjugeret Unconjugated
Arter E. coli
Rekombinant Recombinant
Protein tag His-tag
Sekvens Amino acids Cys24-Ala207 containing an N-terminal His-tag
Indhold og opbevaring -20°C, Avoid Freeze/Thaw Cycles
Udtrykssystem E. coli
Form Liquid
Protein undertype Recombinant
Renhed eller kvalitetsklasse >95%, by SDS-PAGE under reducing conditions
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